which mediated surprisingly long-lasting normalization of insulin resistance through several mechanisms readjusting T cell subsets in diet-induced obese and ob/ob mice.” These findings suggest a ...

This study demonstrates that global or adipose tissue-specific knockout of CIDEC/FSP27 significantly reduces AAA incidence ...

FGH1001 blocked increases in body weight, blood glucose and hepatic fat accumulation in obese ob/ob mice fed a high-fat, high-carbohydrate diet, even under uncontrolled food intake. In working to ...

LPS infusion in normal diet-fed mice causes a metabolic response similar, to some extent, to high-fat feeding. LPS receptor-deleted mice (i.e., CD14 mutants) are hypersensitive to insulin ...

Similarly, hypothalamic ER stress was reduced in the ob–ob obese mouse model, which became sensitive to low doses of leptin. In summary, these findings demonstrate a central role of ER stress in ...

The in vivo localization studies presented here show that CKGGRAKDC targets the white adipose vasculature without a detectable preference for any particular anatomical white fat depot. The uptake ...

Shimon Amir received his PhD in Psychology from McGill University. After completing his postdoctoral training at the Center for Research on Drug Dependence, Concordia University, he joined the ...