While the 2005 Banting Lecture focused on the physiology of ob/ob mice that lack leptin, I will describe variants of these ob/ob mice that span a wide range of body weights. These mice teach us ...

FGH1001 blocked increases in body weight, blood glucose and hepatic fat accumulation in obese ob/ob mice fed a high-fat, high-carbohydrate diet, even under uncontrolled food intake. In working to ...

FGH1001 blocked increases in body weight, blood glucose and hepatic fat accumulation in obese ob/ob mice fed a high-fat, high-carbohydrate diet, even under uncontrolled food intake. In working to ...

The work in mice is firmly established, having now been replicated in two independent laboratories. Studies of the UCP2 promoter polymorphism in other independent human populations are eagerly ...

Similarly, hypothalamic ER stress was reduced in the ob–ob obese mouse model, which became sensitive to low doses of leptin. In summary, these findings demonstrate a central role of ER stress in ...

LPS infusion in normal diet-fed mice causes a metabolic response similar, to some extent, to high-fat feeding. LPS receptor-deleted mice (i.e., CD14 mutants) are hypersensitive to insulin ...

Shimon Amir received his PhD in Psychology from McGill University. After completing his postdoctoral training at the Center for Research on Drug Dependence, Concordia University, he joined the ...

Korea’s largest beer maker Oriental Brewery is seeking to expand its presence in the global soju market amid the rising popularity of the nation’s traditional rice liquor around the world.