Anthony Santander hit a game-ending, two-run homer with two outs in the ninth inning, and the Baltimore Orioles moved closer to a postseason berth with a 5-3 victory over the San Francisco Giants.

Michael Conforto had three hits, including a homer, and the San Francisco Giants frustrated the host Baltimore Orioles again, winning 5-3 on Wednesday night.

The Orioles, 26-30 since the All-Star Game, are now five games back of the New York Yankees in the American League East -- the largest deficit they've faced at any point this season. Baltimore does have a three-game set remaining against the Yankees,